Our research mission is to contribute to the science of聽oral and maxillofacial surgery by integration of research into our practice and training.聽
We currently have many exciting projects involving graduate students, undergraduate students as well as our clinical trainees.聽 These projects are a product of collaborations across several different fields and specialties, resulting in interdisciplinary teams focused on improving outcomes for our patients.聽
Research Publications
2025
Amal Idrissi Janati, Ameena Nizar Beema, Jordan Gigliotti, Nicholas Makhoul, Michel El-Hakim, Nour Karra.(2025). Rates and Determinants of Prosthodontic Rehabilitation After Segmental Jaw Surgery. Journal of oral and Maxillofacial Surgery.聽
Brodeur Audrey, Bach Normand, Zerbo Aisha, Hovey Richard, Idrissi Janati Amal. Can prosthodontic rehabilitation support social eating and return to work in head and neck cancer survivors? A scoping review. J Cancer Surviv. 2025 Aug 2. doi: 10.1007/s11764-025-01861-x. Epub ahead of print. PMID: 40753310.
Upadhyay A, Tsamchoe M, Zeitouni A, Gigliotti J, Peng J, Mahmoodi M, Abo Sharkh H, Makhoul NM, El-Hakim M, Wu J, Tran SD: Extracellular Vesicles of Salivary Mesenchymal Stem Cells Mitigate Acute Irradiation Injury: Use of an ex-vivo organotypic human slice tissue culture as a disease model. bioRxiv 2025.09.04.674343, 2025
Shih H, Khanna M, Thomas J, Makhoul NM, El-Hakim M. Depth of Invasion Threshold for Recommending Elective Neck Dissection in T1 or T2 Oral Squamous Cell Carcinoma. J Oral Maxillofac Surg. 2025 Jan;83(1):102-112. doi: 10.1016/j.joms.2024.10.006. Epub 2024 Oct 18. PMID: 39510128.
2024
Zahavi, S., Ouanounou, Y., Carlen, P., & Ouanounou, A. (2024). Local anaesthetic-induced seizures: a review. Frontiers Of Oral And Maxillofacial Medicine, 7. doi:10.21037/fomm-24-28.聽
Pillai S, Munguia-Lopez JG, Liu Y, Gigliotti J, Zeitouni A, Kinsella JM, Tran SD. Development of human salivary gland cell lines for modeling radiation-induced damage in three-dimensional spheroid cultures. Methods Mol Biol. 2024;2450:39鈥�54. doi:10.1007/978-1-0716-3609-1_4
Amal Idrissi Janati; Jordan Gigliotti; Justin Sanders; Marc Martel; Elham Emami; Nicholas Makhoul; Nour Karra; Anita Brown-Johnson; Agnihotram V. Ramanakuma; Nathalie Gosselin; Lionel Cailhol. (2024). Utilization of Psychosocial Oncology Services by Oral Cancer Patients: a Study Protocol. BMC Public Health.
Cwintal M, Shih H, Idrissi Janati A, Gigliotti J. The effect of the COVID-19 pandemic on the diagnosis and progression of oral cancer. International Journal of Oral and Maxillofacial Surgery. 202; 52: 629-634 doi:10.1016/j.ijom.2024.02.003
Le JM, Gigliotti J, Aljadeff L, Ying YP, Morlandt AB. Airway management in microvascular reconstruction of the oral cavity: is immediate extubation possible? J Oral Maxillofac Surg. 2024;82(10):e1鈥揺2. doi:10.1016/j.joms.2024.10.014
Hashemi S, Psutka D. Internal derangement of the temporomandibular joint. In: Bagheri SC, ed. Clinical Review of Oral and Maxillofacial Surgery. 3rd ed. Mosby/Elsevier; 2024. Chapter 67.
Hashemi, S., & Psutka, D. (2024). Temporomandibular joint ankylosis. In S. C. Bagheri (Ed.), Clinical Review of Oral and Maxillofacial Surgery (3rd ed., Chapter 71). Mosby/Elsevier.
2023
Gourgas, O., Lemire, G., Eaton, A.J. et al. Specific heterozygous variants in MGP lead to endoplasmic reticulum stress and cause spondyloepiphyseal dysplasia. Nat Commun 14, 7054 (2023).
Gigliotti J, Makhoul NM, El-Hakim M. Classification of the Midface Defect. Atlas of the Oral and Maxillofacial Surgery Clinics. 2024 Sept; 32 (2): 73-80. doi:10.1016/j.cxom.2023.12.002
A. M. AlAli, D. Hawkins, S. Glass. Peripheral ameloblastoma underlying squamous cell papilloma following a third molar extraction. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology.
Mascarenhas W, Richmond D, Chiasson G. MRRead鈥擜 Novel Approach to Training Residents in Magnetic Resonance Image Temporomandibular Joint Interpretation. J Oral Maxillofac Surg. 2023;81(6):665-673. doi:10.1016/j.joms.2023.02.003. Accessed August 6, 2024.
Development and Validation of a Novel Craniofacial Statistical Shape Model for the Virtual Reconstruction of Bilateral Maxillary Defects
International Journal of Oral and Maxillofacial Surgery 鈥� Research Article 鈥� Published June 2023
De-Epithelialization Protocol with Tapered Sodium Dodecyl Sulfate Concentrations Enhances Short-Term Chondrocyte Survival in Porcine Chimeric Tracheal Allografts
International Journal of Medical Students 鈥� Research Article 鈥� Published March 2023
Introducing ClinicGPT 鈥� A Custom Large Language Model for Institutional Dental Clinics
Journal of Dental Education 鈥� Research Article 鈥� Published August 2023
Hashemi S, Psutka D. TMJ Ankylosis. Clinical Review of Oral and Maxillofacial Surgery. In Print.
Hashemi S, Psutka D. Internal derangement of the Temporomandibular Joint. Clinical Review of Oral and Maxillofacial Surgery. In Print.
Hashemi S, Psutka D, Caminiti M. Preoperative Internal Maxillary Artery Embolization in the Prevention of Severe Hemorrhage During Total Joint Replacement Surgery. American Society of TMJ Surgeons; Ocean Reef Club, Key Largo, Florida. 2023 Feb
鈥淧alatal Pathology鈥� Chapter 55, in Atlas of Operative Oral and Maxillofacial Surgery, Second Edition.
2022
Le J, Gigliotti J, Sayre KS, Morlandt AB, Ying YY. Supplemental Regional Block Anesthesia Reduces Opioid Utilization Following Free Flap Reconstruction of the Oral Cavity: A Prospective, Randomized Clinical Trial. Journal of Oral and Maxillofacial Surgery. 2023 Feb;81(2):140-149.
Idrissi Janati, I. Karp, D. Von Renteln, M. Bouin, Y. Liu, S D. Tran, E. Emami. (2022). Investigation of Fusobacterium Nucleatum in saliva and colorectal mucosa: a pilot study. Scientific Reports, 12(1):5622.
Idrissi Janati, I. Karp, J鈥慒 Latulippe, P. Charlebois, E. Emami. (2022). Periodontal disease as a risk factor for sporadic colorectal cancer: results from COLDENT study. Cancer Causes Control, 33(3):463-472.
H. Morsi, M. Golizeh, N. Brosseau, A. Idrissi Janati, E. Emami, M. Ndao, S D. Tran. (2022). Detection of Fusobacterium nucleatum subspecies in the saliva of pre-colorectal cancer patients, using tandem mass spectrometry. Archives of Oral Biology, 134 (2022)-105337.
2021
Rapid development of a novel and open-access mixed reality resource for dental education
Journal of Dental Education 鈥� Research Article 鈥� Published September 2021
A.M. AlAli. Surgical Wire Twisting Tool (USA). United States Patent and Trademark Office Grant. Surgical wire twisting tool, US11083510B1, filed Apr 19, 2021, and published Aug 10, 2021.
A.M. AlAli, T.H. AlAnzi. Inferior alveolar nerve damage secondary to orthodontic treatment: A systematic scoping review. The International Journal of Risk and Safety in Medicine
A.M. AlAli, H.H.H. Ibrahim, A. Algharib, F. Alsaad, B. Rajab. Characteristics of pediatric maxillofacial fractures in Kuwait: A single- center retrospective study. Dental Traumatology
A.M. AlAli, H. Nazar. Preferences, perception, and impact of using dental social media in Kuwait. Kuwait Medical Journal
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M. Abdulwahab, M. Kamal, A.M. AlAli, Y.M. Husain, M. Safar. Knowledge and Perceptions of COVID-19 Among Health Care Professionals, Medical Students, and Dental Students in the GCC Region: A Cross-Sectional Correlational Study. Journal of Multidisciplinary Healthcare
M. Abdulwahab, M. Kamal, A.M. AlAli. Assessment of Nitrous Oxide Inhalation Sedation Module in Kuwait: A Survey on Undergraduate Dental Training Curriculum. Advances in Medical Education and Practice
Baabdullah R, Gigliotti J, Makhoul N, Jung S. Desmoid fibromatosis of the maxillofacial region: A case report and review of the literature. Oral Surgery. 2021.
Hashemi S, Ferraz Dos Santos B, Chiasson G. Does the Transversus Abdominis Plane Block Reduce Morbidity Following Iliac Crest Bone Harvest in Pediatric Patients With Alveolar Clefts? Cleft Palate Craniofac J. 2021 Nov.
Gigliotti J, Ying Y, Redden D, Kase M, Morlandt AB. Fasciocutaneous Flaps for Refractory Intermediate Stage Osteoradionecrosis of the Mandible鈥擨s It Time for a Shift in Management? J Oral Maxillofac Surg 2021;79:1156-1167.
Le JM, Morlandt AB, Gigliotti J, Park EP, Greene BJ, Ying YP. Complications in oncologic mandible reconstruction: A comparative study between the osteocutaneous radial forearm and fibula free flap. Microsurgery. 2021;1-10.
Le JM, Gigliotti J, Ying Y, Kase MT, Morlandt AB. Computer-Assisted Microvascular Free Flap Reconstruction and Implant Rehabilitation of the Maxilla鈥擳reatment of a Rare Post-orthognathic Complication J. Maxillofac. Oral Surg 2021.
Park EP, Minh Le J, Gigliotti J, Feinstein J, Ying YP, Morlandt AB. Does Supplemental Regional Anesthesia Decrease Length of Stay and Opioid Use for Patients Undergoing Head and Neck Microvascular Reconstruction? J Oral Maxillofac Surg 2021; 79:712-721
2020
Gigliotti J, Ying Y, Morlandt AB. Titanium alloy cutting guides in craniomaxillofacial surgery- a minimally invasive alternative to synthetic polymer guides. Journal of Oral and Maxillofacial Surgery. 2020;78:2080-2089.
A.M. AlAli, T. Walsh, M. Maranzano. CYFRA 21-1 and MMP-9 as salivary biomarkers for the detection of oral squamous cell carcinoma (OSCC): A systematic review of diagnostic test accuracy. International Journal of Oral and Maxillofacial Surgery
A.M. AlAli, H. Dashti, Y. Al-Yahya, H. Ali. A report of two atypical genetic cases of cherubism: Reduced penetrance and sporadic occurrence. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology.
Hussein H.H. Ibrahim, A.M. AlAli, P. Sch眉tz, B. Rajab. Transantral approach for surgical removal of impacted maxillary second premolar located in trifurcation of molar roots: A case report - Oral Surgery.
Farsi NJ, Merdad Y, Mirdad M, Batweel O, Badri R, Alrefai H, Alshahrani S, Tayeb R, Farsi J. Oral Health Knowledge, Attitudes, and Behaviors Among University Students in Jeddah, Saudi Arabia. Clin Cosmet Investig Dent. 2020;12:515-523
Idrissi Janati, I. Karp, C. Laprise, H. Sabri, E. Emami. (2020). Detection of Fusobacterium nucleatum in feces and colorectal mucosa as a risk factor for colorectal cancer: a systematic review and meta-analysis. Systematic Reviews, 9(1):276.
2019
Idrissi Janati, I. Karp, Hisham Sabri, E. Emami. (2019). Is Fusobacterium nucleatum infection in the colon a risk factor for colorectal cancer? A systematic review and meta-analysis protocol. Systematic Reviews, 8(1):114.