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UID:20260425T210104EDT-5906NAaoKH@132.216.98.100
DTSTAMP:20260426T010104Z
DESCRIPTION:\nSupported by the generosity of the Killam Trusts\, The Neuro'
 s Killam Seminar Series invites outstanding guest speakers whose research 
 is of interest to the scientific community at The Neuro and 91ËżąĎĘÓƵ Univers
 ity.\n\n\nRegister Now\n\nTo watch online\, click here\n\nHost: \n\n\nThe 
 neural basis of flexible\, lifelong learning\n\nAbstract: I will present r
 ecent work demonstrating that the auditory cortex (AC) is necessary for so
 und discrimination learning but dispensable at expert levels. Rather than 
 reflecting changes in sensory tuning or map expansion\, learning and perfo
 rmance rely on distinct higher-order computations—reward prediction for le
 arning and action suppression to enable stable performance—implemented by 
 spatially clustered neural ensembles. These clusters are orthogonal to cla
 ssic stimulus-tuning\, revealing an organizational principle that extends 
 beyond sensory coding. I will close by shifting from single-task learning 
 to our developing framework for studying lifelong\, multi-task learning in
  mice\, centered on our Continual Learning Mouse Playground: a fully autom
 ated\, high-throughput home-cage environment in which mice learn a progres
 sion of perceptual\, contextual\, and compositional tasks over months. Thi
 s platform enables us to investigate how biological brains acquire\, reuse
 \, and recombine knowledge across the lifespan\, with a particular focus o
 n the mechanisms supporting compositionality and generalization.\n\nKishor
 e V. Kuchibhotla\n\nAssociate Professor at Johns Hopkins University\n\nI w
 ill present recent work demonstrating that the auditory cortex (AC) is nec
 essary for sound discrimination learning but dispensable at expert levels.
  Rather than reflecting changes in sensory tuning or map expansion\, learn
 ing and performance rely on distinct higher-order computations—reward pred
 iction for learning and action suppression to enable stable performance—im
 plemented by spatially clustered neural ensembles. These clusters are orth
 ogonal to classic stimulus-tuning\, revealing an organizational principle 
 that extends beyond sensory coding. I will close by shifting from single-t
 ask learning to our developing framework for studying lifelong\, multi-tas
 k learning in mice\, centered on our Continual Learning Mouse Playground: 
 a fully automated\, high-throughput home-cage environment in which mice le
 arn a progression of perceptual\, contextual\, and compositional tasks ove
 r months. This platform enables us to investigate how biological brains ac
 quire\, reuse\, and recombine knowledge across the lifespan\, with a parti
 cular focus on the mechanisms supporting compositionality and generalizati
 on.\n
DTSTART:20260526T200000Z
DTEND:20260526T210000Z
LOCATION:de Grandpre Communications Centre\, The Neuro\, Montreal Neurologi
 cal Institute\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Killam Seminar Series: The neural basis of flexible\, lifelong lear
 ning
URL:/wholepersoncare/channels/event/killam-seminar-ser
 ies-neural-basis-flexible-lifelong-learning-372040
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