Jeremy Van Raamsdonk, PhD, MSc
Associate Professor
My research focuses on the genetics and biology of aging and the pathogenesis of neurodegenerative disease. I am also highly interested in biological resilience and how that contributes to longevity and neurodegeneration. Much of my work focusses on the mitochondria as it is highly involved in lifespan, resilience and neurodegenerative disease. To complete these studies, I primarily use a simple genetic model organism, the worm C. elegans. My work in geroscience aims to advance our understanding of the molecular mechanisms underlying longevity and biological resilience and apply that knowledge to promote healthy aging and develop novel treatments for neurodegenerative disease. I use a translational approach in which we perform initial experiments in C. elegans in order to prioritize subsequent experiments in mammalian models.
Di Pede A, Ko B, AlOkda A, Tamez Gonz谩lez AA, Zhu S, Van Raamsdonk JM. Open Biol. 2025 Apr;15(4):240358. doi: 10.1098/rsob.240358. Epub 2025 Apr 2.PMID: 40169016
Liontis T, Senchuk MM, Zhu S, Jacob-Tomas S, Anglas U, Traa A, Soo SK, Van Raamsdonk JM. Free Radic Biol Med. 2025 Mar 1;229:195-205. doi: 10.1016/j.freeradbiomed.2025.01.032. Epub 2025 Jan 17.PMID: 39827921
Traa A, Tamez Gonz谩lez AA, Van Raamsdonk JM. Geroscience. 2025 Feb;47(1):877-902. doi: 10.1007/s11357-024-01276-z. Epub 2024 Jul 19.PMID: 39028454
Traa A, Keil A, AlOkda A, Jacob-Tomas S, Tamez Gonz谩lez AA, Zhu S, Rudich Z, Van Raamsdonk JM. Aging Cell. 2024 Oct;23(10):e14262. doi: 10.1111/acel.14262. Epub 2024 Jul 2.PMID: 38953684
Soo SK, Rudich ZD, Ko B, Moldakozhayev A, AlOkda A, Van Raamsdonk JM. Ageing Res Rev. 2023 Jul;88:101941. doi: 10.1016/j.arr.2023.101941. Epub 2023 Apr