BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20251208T074103EST-6773pUgNkG@132.216.98.100 DTSTAMP:20251208T124103Z DESCRIPTION:\nThe Neuro Epilepsy Day 2026: Epilepsy Across Multiple Scales  \n\nThe Neuro Epilepsy Day will be a full-day program\, exploring epilepsy research and treatment across all scales: molecular\, cellular\, circuit\ , and connectome.\n\n\nRegistration coming soon.\n\n\nCall for Abstracts\n \nWe invite undergraduate\, graduate\, and postdoctoral trainees to submit abstracts for poster presentations at Neuro Epilepsy Day 2026. \n\nWe enc ourage abstracts at any stage of a project’s development—from literature r eviews and research questions to pilot data and ongoing studies.\n\nSubmis sion deadline: March 23\, 2026\n\nSubmit Your Abstract Here\n\nSelected ab stracts will be featured in the poster session\, and five outstanding post ers will be invited to give a short oral presentation during the program. \n\n\n\n \n Programme\n Speakers\n The Pierre Gloor Lecture\n Location\n Sponsor s\n Scientific Committee\n \n\n \n Thursday\, May 28\, 2026\n\n Preliminary Pro gram \n\n \n \n \n 9:15\n \n Arrival & Registration\n \n \n \n 9:30\n \n Lab Tours\n\n Neuroimaging\, EEG/FMRI\, MEG\,\n \n \n \n 10:45\n \n Welcome and Introduction\n \n Boris Bernhardt\, PhD\n Associate Professor of Neurology and Neurosurgery \n Epilepsy Group Leader (Research)\, The Neuro\n \n \n \n 11:00\n \n Keynote Lec tures\n\n Improving Epilepsy Surgery Planning Using MR Fingerprinting\n\n Ir ene Wang\, PhD\n Research Director and Staff Scientist\n Cleveland Clinic Ep ilepsy Center\n\n  \n\n Networks\n\n Seok-Jun Hong\, PhD\n Associate Professor of Biomedical Engineering Department\, SKKU\n Sungkyunkwan University - Mc Gill University\n\n  \n\n Surgical Perspectives\n\n Roy William Dudley\, FRCS C\n Assistant Professor\, Department of Pediatric Surgery\, Department of N eurology & Neurosurgery\n Montreal Children's Hospital\n\n  \n\n Alexander G. Weil\, FRCSC\, FACS\n Associate Professor\, Neurosurgeon\, Researcher\, Di rector\n University of Montreal - Sainte-Justine Hospital Research Centre\n \n  \n\n Jeffery Allan Hall\, FRCSC\n Assistant Professor of Neurology and Ne urosurgery\n Epilepsy Programme\, Neurosurgery Clinic\, Brain Tumour Clinic \n \n \n \n 1:00\n \n Lunch and Poster Session\n \n \n \n 2:00\n \n Oral Presentations \n \n \n \n 3:00\n \n Coffee Break\n \n \n \n 3:15\n \n Pierre Gloor Lecture\n\n Brain Mosaicism in Epilepsies and Cortical Malformations\n Stéphanie Baulac\, PhD \n Research director and Group Leader\n Inserm and Paris Brain Institute (IC M)\n \n \n \n 4:15\n \n Discussion Panel\n\n \n Stéphanie Baulac\, PhD\n Research d irector and Group Leader Inserm and Paris Brain Institute (ICM)\n \n\n \n Bor is Bernhardt\, PhD\n Associate Professor of Neurology and Neurosurgery\n Hea d of Multimodal Imaging and Connectome Analysis Lab\n \n\n \n Raluca Pana\, M D\, FRCP\, CSCN\n Neurologist and epileptologist at The Neuro and Assistant Professor in the Department of Neurology and Neurosurgery of the Faculty of Medicine at 91Ë¿¹ÏÊÓƵ.\n \n\n \n Myriam Srour\, MDCM\, PhD\n Associ ate Professor\, Department of Pediatrics\, 91Ë¿¹ÏÊÓƵ.\n \n\n \n Alexa nder Barnett\, PhD\n Assistant Professor at the Montreal Neurological Insti tute.\n \n\n \n Samantha Audrain\, PhD\n Assistant Professor in Behavioral Neu roscience\n \n\n \n Sara Lariviere\, PhD \n Assistant Professor at Sherbrooke University\n \n\n \n Andrea Bernasconi\, MD\n Neurologist and Epileptologist s pecialized in Neuroimaging of Epilepsy.\n \n\n \n Neda Labdon-Bernasconi\, Ph D\n Neuroscientist specialized in Neuroimaging of Epilepsy\;\n Co-founder of the Neuroimaging of Epilepsy Laboratory (NOEL)\n \n \n \n \n 5:00\n \n Cocktail Reception (onsite)\n \n \n \n \n \n\n \n Speakers\n\n Keynotes:\n\n Irene Wang | MR I/Clinical\n\n Dr. Irene Wang is the Research Director and Full Staff at th e Cleveland Clinic Epilepsy Center and an Associate Professor of Neurology at the Cleveland Clinic Lerner College of Medicine. Her research advances surgical treatments for MRI-negative epilepsy patients through innovative imaging and neurophysiology techniques. As a trained biomedical engineer with a strong foundation in clinical neurophysiology and neuroimaging\, Dr . Wang has pioneered the integration of advanced imaging into clinical pra ctice to enhance patient care. She has authored over 120 peer-reviewed pap ers and serves as Associate Editor for Epilepsia. Dr. Wang has received co ntinuous support from the National Institute of Health and serves as a cha rter member of the NIH Imaging Technology for Neuroscience study section. Dr. Wang also chairs the MRI Data Task Force of the ILAE Big Data Commissi on and serves on the Imaging Task Force of the ILAE Diagnostic Methods Com mission.\n \n Improving Epilepsy Surgery Planning Using MR Fingerprinting\n M ore details to come...\n\n  \n\n Stéphanie Baulac | Pierre Gloor Lecture\n\n Stéphanie Baulac is a Research Director at Inserm and Group Leader at the Paris Brain Institute (ICM) of the MOSAIC Team « Genetic Mosaicism in Epil epsy and Neurodevelopmental Disorders » Her team implements a comprehensiv e translational approach spanning from the identification and characteriza tion of somatic mutations in brain tissues obtained from patients undergoi ng epilepsy surgery to in-depth functional analysis\, combining functional testing on patient-derived brain organoids\, and mouse models. \n \n Brain Mosaicism in Epilepsies and Cortical Malformations\n Focal cortical dysplas ia type II (FCDII) is a cortical malformation causing refractory epilepsy\ , resulting from developmental somatic mutations in mTOR pathway genes. To understand how these mutations create a mosaic pattern of affected cells and lead to cortical dyslamination\, we performed comprehensive single-nuc leus analyses of surgical samples from genetically-characterized FCDII pat ients. By combining genotyping and transcriptomics at single-cell resoluti on\, we revealed that mutations predominantly affect glutamatergic neurons and astrocytes\, creating distinct transcriptional programs in both mutat ed and non-mutated cells. This mosaicism drives cell-type-specific dysregu lation of synaptic and neurodevelopmental pathways that likely contribute to epileptogenesis. Notably\, our analysis of cytomegalic cells uncovered pronounced alterations in mitochondrial metabolism pathways and cellular s enescence. We uncover a signature associated with cellular senescence in a bnormal FCDII cells and further provide evidence in preclinical FCDII mous e models that senolytic agents could offer a novel therapeutic strategy fo r this disorder.\n\n  \n\n \n \n\n \n The Pierre Gloor Lecture\n\n The Pierre Gl oor Lecture celebrates the life and legacy of Pierre Gloor (1923–2003)\, w ho joined The Neuro (Montreal Neurological Institute-Hospital) in 1952 as a fellow in electroencephalography and neurophysiology. He trained under W ilder Penfield and Herbert Jasper and earned his PhD from 91Ë¿¹ÏÊÓƵ Universit y in 1957. Gloor collaborated closely with clinical and research teams at The Neuro in advancing the understanding and treatment of epilepsy\, gaini ng international recognition for his contributions to the field.\n\n Brain Mosaicism in Epilepsies and Cortical Malformations\n\n Speaker: Stéphanie B aulac\, PhD\n Research director and Group Leader\n Inserm and Paris Brain In stitute (ICM)\n\n Focal cortical dysplasia type II (FCDII) is a cortical ma lformation causing refractory epilepsy\, resulting from developmental soma tic mutations in mTOR pathway genes. To understand how these mutations cre ate a mosaic pattern of affected cells and lead to cortical dyslamination\ , we performed comprehensive single-nucleus analyses of surgical samples f rom genetically-characterized FCDII patients. By combining genotyping and transcriptomics at single-cell resolution\, we revealed that mutations pre dominantly affect glutamatergic neurons and astrocytes\, creating distinct transcriptional programs in both mutated and non-mutated cells. This mosa icism drives cell-type-specific dysregulation of synaptic and neurodevelop mental pathways that likely contribute to epileptogenesis. Notably\, our a nalysis of cytomegalic cells uncovered pronounced alterations in mitochond rial metabolism pathways and cellular senescence. We uncover a signature a ssociated with cellular senescence in abnormal FCDII cells and further pro vide evidence in preclinical FCDII mouse models that senolytic agents coul d offer a novel therapeutic strategy for this disorder.\n\n  \n\n \n \n\n \n Lo cation\n\n The Montreal Neurological Institute and Hospital is at 3801 Univ ersity Street\, north of Pine Avenue West\, on the 91Ë¿¹ÏÊÓƵ campu s opposite the former Royal Victoria Hospital.\n\n Montreal is served by hi ghway Routes 10\, 15\, 20 and 40\, and by Greyhound Bus\, Via Rail and the P-E-Trudeau airport. In the city\, bus and metro service is provided by t he Société de transport de Montréal (STM).\n\n Wheelchair access\n\n A wheel chair accessible entrance is on University Street north of the main entran ce. Another wheelchair accessible entrance is in the loading area behind t he building: to enter the loading area\, turn into the driveway south of t he main entrance. Please note\, there is no parking in the loading area.\n \n Parking\n\n Parking near the MNI is sometimes difficult. There are parkin g meters on University Street and a parking lot north of the main entrance . To enter the lot\, turn right into the driveway toward Molson Stadium.\n \n Information about parking fees\n\n Taxi Stand\n\n There is a taxi stand on University Street across from the main entrance. You may call a cab from the free taxi phone in the main lobby near the Security Desk.\n\n Access by Public Transportation (STM website)\n\n Bus\n\n There are four bus stops wi thin walking distance:\n\n \n Bus 144 stops at Pine Avenue and University St reet\n Bus 356 stops at Sherbrooke Street and University Street (Nightbus) \n Bus 107 stops at Pine Avenue and Docteur Penfield\n Bus 24 stops at Sherb rooke Street and University Street\n \n\n Metro\n\n Take the Metro Green Line to the 91Ë¿¹ÏÊÓƵ station. Walk north on University Street and cross Pine Ave nue. The main entrance is on the right\, past the flags.\n\n Jeanne Timmins Amphitheatre\n\n \n Enter the main lobby\, turn left\, and go down the hall way to the end.\n Turn right and go down the second hallway until you see a nother hallway on the left.\n This hallway leads to the Jeanne Timmins Foye r.\n On your right are the Jeanne Timmins Amphitheatre entrance doors.\n \n \n\n \n Sponsors \n \n\n \n Scientific Committee\n\n Sam Audrain\n\n Alexander Ba rnett\n\n Boris Bernhardt\n\n Sara Larivière\n\n Raluca Pana\n\n Debbie Rashco vsky\n\n Myriam Srour\n\n  \n\n \n \n\n DTSTART:20260528T131500Z DTEND:20260528T210000Z LOCATION:Jeanne Timmins Amphitheatre\, The Neuro SUMMARY:The Neuro Epilepsy Day 2026: Epilepsy Across Multiple Scales URL:/neuro/channels/event/neuro-epilepsy-day-2026-epil epsy-across-multiple-scales-368975 END:VEVENT END:VCALENDAR