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UID:20260803T012415EDT-6557Gfhtvv@132.216.98.100
DTSTAMP:20260803T052415Z
DESCRIPTION:Dense collagen construct as a tubular tissue\nmodel\nDue to the
  intrinsic complexity of tissues and organs\, only\nplanar tissues have ac
 hieved clinical applications in tissue\nengineering. In contrast\, tissue 
 engineered tubular constructs\npresent a complex geometry and architecture
 \, limiting the\naccomplishment of suitable substitutes. Type I collagen i
 s an\noptimal candidate for scaffolding due to the high biocompatibility\n
 and processability. However\, collagen based hydrogels exhibit\nunstable g
 eometrical properties\, due to cell-mediated contraction\,\nand low mechan
 ical properties\, requiring additional modifications.\nPlastic compression
  (PC) technique rapidly produces dense collagen\nconstructs with fibrillar
  densities equivalent to native tissue. In\nthis study\, by application of
  PC a tubular dense collagen construct\nwas developed and characterized\, 
 and the effect of different\ncollagen densities and diverse collagen sourc
 es were investigated.\nMoreover\, the dense tubular construct was seeded w
 ith primary\nairway smooth muscle cells extracted and cell viability\, ali
 gnment\,\nproteins expression and scaffold morphology were studied under\n
 static and dynamic culture conditions.\n
DTSTART:20110401T190000Z
DTEND:20110401T190000Z
LOCATION:Wong Building\, CA\, QC\, Montreal\, H3A 0C5\, 3610 rue University
SUMMARY:Graduate Seminar - Chiara Ghezzi\, PhD Candidate
URL:/channels/event/graduate-seminar-chiara-ghezzi-phd
 -candidate-173407
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