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UID:20260803T200719EDT-73566s56hb@132.216.98.100
DTSTAMP:20260804T000719Z
DESCRIPTION:Nanomechanical Resonator Arrays for the\nSpecific Detection of 
 Proteins\nDetection of biological and chemical agents is critical to many
 \nlife sciences areas including disease diagnosis\, drug molecule\nscreeni
 ng\, and rapid analysis of various molecular systems. Micro-\nand nanoreso
 nators have also been shown to be promising platforms\nfor such tagless an
 alysis. The mass sensitivity of mechanical\nresonators scales favorably as
  their mass is reduced\, offering a\ncompelling path for the development o
 f large arrays of devices\noffering exceptional sensitivities. An overview
  of activities\nconcerning the development of such nanoresonator arrays wi
 ll be\npresented. In a first approach\, we have developed a novel surface
 \nnanomaching procedure allowing the fabrication of resonators as\nnarrow 
 as 15 nm with a yield approaching 100%. This approach also\ndoes not requi
 re a critical point drying step which is known to\nleave residues onto the
  device surfaces. Alternatively\, the last\nfew years have also seen the d
 evelopment of alternate 'bottom-up'\ntechniques for the fabrication of nan
 odevices. For example\, silicon\nnanowires have been used to detect biolog
 ical and chemical species.\nThese sensors operate by monitoring changes of
  electrical\nconductivity associated to the binding. In this work\, the sp
 ecific\ndetection of proteins using nanowires was rather achieved through
 \nthe monitoring of their mechanical resonance. The read-out of both\nsurf
 ace-machined and surface-grown nanowires was performed using an\nall-optic
 al method of actuation and detection\, preventing the need\nof electrical 
 contacts to the individual devices. The specific\ndetection of streptavidi
 n using biotin as molecular probe was\ndemonstrated as proof of concept in
  both types of devices.\nDr. Stephane Evoy (NINT/UofA) received a B. Ing\n
 and M.Sc.A in Engineering Physics from the Ecole Polytechnique de\nMontréa
 l\, in 1992 and 1994\, respectively. He also received Ph.D. in\nApplied Ph
 ysics from Cornell University in 1998. He is currently an\nAssociate Profe
 ssor in the Department of Electrical and Computer\nEngineering at the Univ
 ersity of Alberta\, as well as a Principal\nInvestigator - Devices and Sen
 sors at the National Institute for\nNanotechnology in Edmonton. Dr. Evoy h
 as co-authoredover 60 papers\nand presentations in the area of nanoelectro
 mechanical systems\n(NEMS)\,nanosensors\, nanofabrication\, and scanning p
 robe microscopy.\nHe co-edited the 2004 textbook:'Introduction to Nanoscal
 e Science\nand Engineering.' His own research currently focuses on cantile
 ver-\nand SPR-based detection of proteins and pathogens\, as well as the\n
 development of bioassay platforms based on large arrays of\nnanomechanical
  resonators.\n
DTSTART:20100309T150000Z
DTEND:20100309T160000Z
LOCATION:Wong Building\, CA\, QC\, Montreal\, H3A 0C5\, 3610 rue University
SUMMARY:Invited Speaker - Stephane Evoy
URL:/channels/event/invited-speaker-stephane-evoy-1150
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