BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260801T212609EDT-0527gpRj6w@132.216.98.100 DTSTAMP:20260802T012609Z DESCRIPTION:The siren song of cancer cells – lies\, deceit and\nmisinformat ion in cellular communication underlying disease.\nBy Janusz Rak (Jack Col e Chair in Pediatric\nHematology/Oncology and Associate Professor\, Depart ment of\nPediatrics\, 91Ë¿¹ÏÊÓÆµ).\nAn effective treatment of compl ex diseases\, especially cancer\,\nmay lie in grasping their mechanisms at different levels of\nbiological hierarchy. While much research currently concentrates on\nunderstanding how various genes cause cancer from within a cell\,\nmuch can be learnt from studies on what happens between cells\, and\nin their relations to their surroundings. In this regard\, cancer\nce lls are not only ‘antisocial’\, but also exhibit a ‘gang culture’\,\nwhere by they act in concert to achieve certain pathological ends.\nThis is illu strated by ‘coercion’ of normal tissues\, such as blood\nvessels or bone m arrow\, to collaborate with the tumour cell group\,\nand in ‘corrupting’ i nfluences within it. These influences are\nexerted through several means o f abnormal cell-to-cell\ncommunication\, one of which is sending cancer-ca using proteins\n(oncoproteins) toward other cells in a form of structures called\nmicrovesicles. The latter can trigger aberrant behaviour of\nother wise non-aggressive cells\, which makes them a part of the\ndisease proces s. The challenge is to learn more about and from\nmicrovesicles\, and ulti mately block the ‘siren song’ of cancer\ncells.\n\nOrganized since 2003 wi th the express purpose of fostering\ncommunication between scientists in d ifferent disciplines as well\nas between scientists and the public\, the C utting\nEdge Lectures in Science are made possible\nthrough the generous s upport of Heather Munroe-Blum (91Ë¿¹ÏÊÓÆµ\nPrincipal)\, Richard Levin (Dean of Medicine)\, Martin Grant (Dean of\nScience)\, Anthony Masi (Provost) and Denis Thérien (Vice-Principal\,\nResearch and International Relations). Le ctures are followed by\na vin d'honneur reception. Free\, everyone welcome .\n DTSTART:20100114T230000Z DTEND:20100114T230000Z LOCATION:Redpath Museum\, CA\, QC\, Montreal\, H3A 0C4\, 859 rue Sherbrooke Ouest SUMMARY:Cutting Edge Lectures in Science URL:/channels/event/cutting-edge-lectures-science-1084 75 END:VEVENT END:VCALENDAR